Updated: Feb 4, 2022
CryoDerm is a relatively new kid on the block, having been launched in 2000 by the Florida-based company Alternative Health Care Ventures.
The company's mission is to, "bring the highest quality, most effective topical Pain Relievers to the medical market." They also use only recycled packaging and have a commitment to no animal testing.
MENTHOL
Menthol makes up approximately 10% of CryoDerm Cold Therapy. In CryoDerm Heat Therapy, it makes up approximately 4%. This organic compound is made synthetically or obtained from mint oils; in this case it is from peppermint oil.
Menthol stimulates the transient receptor potential channel melastatin 8 (TRPM8). This receptor is responsible for the well-known cooling sensation it provokes when inhaled, eaten, or applied to the skin.
It also has weak analgesic (pain-killing) effects due to its selective activation of our κ-opioid receptor. This protein mediates many effects including changing our perception of pain, consciousness, motor control, and mood.
CAMPHOR
Camphor is present in the CryoDerm Heat Therapy product.
This waxy solid has a strong aromatic odor. It is found in the wood of the evergreen tree Cinnamomum camphora; Dryobalanops aromatica; Ocotea usambarensis; and dried rosemary leaves (Rosmarinus officinalis). It's easily absorbed through skin and produces a cool-feeling like menthol.
There are no known major side effects for using Tiger Balm topically (on the skin, external use only). Although one should seek medical attention if severe allergic reaction occurs. Not a good idea to use on broken or damaged skin, and be sure to keep it clear of the eyes - ouch.
I found an established body of research that may suggest the use of menthol for mild pain relief and anti-inflammatory effects. Given the very low risk and very limited side effects, it would seem worth a try for individuals seeking a complementary product for pain relief.
Via Amazon, you can purchase the CryoDerm Cold Therapy roll-on, spray, or gel and the CryoDerm Heat Therapy roll-on or gel. And if you can't decide between the two, you can purchase a combo roll-on pack.